The Scientist's articles under the category: Biochemistry. Researchers examine how long-term exposure to widely used per- and polyfluoroalkyl substances (PFAS) detrimentally affect human health.

Welcome to Words for Nerds, our popular and addictive daily science word game. Think of it as science Wordle—a guessing jumble for every nerd, especially the busy life scientist looking to get a little break from the rigors of research. You have six chances to guess either a …

This webinar will be hosted live and available on-demand. Monday, December 16th, 2024 12:30 - 2:00 PM ET . Targeted therapies are transforming the medical field by enabling clinicians to precisely and effectively treat patients with serious diseases.

The Scientist Magazine®'s published issues. New Approaches for Decoding Cancer at the Single-Cell Level. In this webinar, Linghua Wang and Jeremy Goecks will talk about technology that enables new approaches for a better understanding of tumors on a cellular, spatial, and environmental level.

The Scientist's Crossword Puzzles articles. Put on your thinking cap, and take on this fun challenge. Put on your thinking cap, and take on this fun challenge.

A.B. Pardee, "G1 events and regulation of cell proliferation," Science, 246, 603-8, 3 November 1989. Arthur Pardee (Dana-Farber Cancer Institute, Boston): "This review summarizes background concepts and facts that led to the recent explosive interest in the mechanisms of cell proliferation [The Scientist, Dec. 10, 1990, page 15]. Maturation of this subject was recognized by publication of six ...

C re-loxP recombination allows scientists to excise, insert, or invert specific DNA segments with unprecedented accuracy. 1,2 This works through two key components: a Cre recombinase and loxP sequence recognition sites. The Cre enzyme identifies pairs of loxP sites (arrowheads), which flank (flox) the DNA, and catalyzes reciprocal DNA recombination between the two sites to excise a small piece ...

Sternberg pondered about the underlying mechanism; he suspected that there must be a genetic hotspot for recombination located at the terminal ends of the linear genome to facilitate plasmid cyclization. 1. The genesis of Cre-loxP recombinationConsistent with his hypothesis, Sternberg’s experiments revealed a small fragment of P1 DNA at the end of …

The Scientist has asked a group of experts to periodically comment upon recent articles that they have found noteworthy. Their selections, presented here in every Issue, are neither endorsements of content nor the result of systematic searching. Rather, they are personal choices of articles they believe the scientific community as a whole may also find interesting. Reprints of …

PETER D. MOORE Department of Biology King's College London, U.K. Intensive exploitation of fish stocks in the Amazon basin has exhausted the supply of large fish and has led to increasing pressure being placed on smaller fish, such as the jaraqui. But there is an urgent need for coordinated management if yields are to be sustainable. A closed spawning season and protection during the ...