There are 11 ways to get from Santa Ana to San Francisco by train, plane, bus, subway, night bus (Flixbus), bus (Greyhound), or car. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Santa Ana and San Francisco are 6 hours 14 mins far apart, if you drive non-stop . This is the fastest route from Santa Ana, CA to San Francisco, CA. The halfway point is Avenal, CA. Santa Ana, CA and San Francisco, CA are in the same time zone (PDT). Current time in both locations is …

7 trains operate daily from Santa Ana to San Francisco. The train trip from Santa Ana to San Francisco is usually about 12 hours and 11 minutes long. However, traveling on the fastest Amtrak train can get you there in as little as 11 hours and 15 minutes.

There are 12 ways to get from San Francisco to Santa Ana by plane, subway, bus, train, night bus (Flixbus), bus (Greyhound), or car. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

There are 10 ways to get from Santa Ana to San Francisco, CA by train, plane, subway, bus or car. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Flights from Santa Ana to San Francisco. Use Google Flights to plan your next trip and find cheap one way or round trip flights from Santa Ana to San Francisco.

Fly one-way from Orange County/Santa Ana to San Francisco (SFO) starting at $178. Bundle your Southwest Airlines® flight with a hotel or rental car booking and find even more savings.

Find cheap fares from Santa Ana, CA (SNA) to San Francisco, CA (SFO) with Frontier Airlines. Enjoy unlimited savings all year with the Discount Den℠!

The top stops along the way from Santa Ana to San Francisco (with short detours) are Universal Studios Hollywood, Venice, and Griffith Observatory. Other popular stops include Six Flags Magic Mountain, Santa Monica Pier, and Knott's Berry Farm.

Use the road trip planner to drive from Santa Ana to San Francisco using the best route and find places to stop.