The climactic battle between Hulk (Edward Norton) and the Abomination (Tim Roth) takes place in Harlem at the end of "The Incredible Hulk", and in "Captain America: Brave New World" we learn the neighborhood may not have survived the battle. Harlem is referred to as being destroyed twice.

Brave New World underwent a variety of changes and tweaks, something a number of big-budget movies have gone through over the years. In addition to a title change, production was paused on the film due to the 2023 actors’ and writers’ strikes,

Actor Tim Blake Nelson's wonderfully goofy take on the Leader helps forgive a lot of the clunkier parts of Brave New World. But the character would have been so much more impressive had it followed the model set by the groundbreaking comic book series The Immortal Hulk.